microcytic anemia in children with phenylketonuria in tehran

sixty-nine children with phenylketonuria (pku) under coverage of tehran genetic research andconsultation center, fed lofenalac and phenylfree were studied. the 24-hour dietary recall method was usedto determine food intake and blood samples were analyzed for iron parameters. the results showed that over7% of the children had a low intake of energy, protein and iron. in addition, hemoglobin and hematocrit werelower than normal in 3.1% of the children, while in 24.2% of them there was decreased serum transferrinsaturation percent. there was a statistically significant relationship between lenght of diet therapy and ironparameters. the findings show that inadequate nutrient intakes may, over time, cause appearance of anemia signs in the children with pku dependent on special formulations